Area of Study
|
References
|
Fatigue
|
· Del Rio C, Collins LF,
Malani P. Long-term Health Consequences of COVID-19. JAMA. 2020 Oct 5. doi:
10.1001/jama.2020.19719
· Greenhalgh T, Knight M,
A'Court C, Buxton M, Husain L. Management of post-acute covid-19 in primary
care. BMJ. 2020 Aug 11;370:m3026.
· Carfì A, Bernabei R, Landi
F; Gemelli Against COVID-19 Post-Acute Care Study Group. Persistent Symptoms
in Patients After Acute COVID-19. JAMA. 2020 Aug 11;324(6):603-605.
· Tenforde MW, Kim SS, Lindsell CJ, et al.
Symptom Duration and Risk Factors for Delayed Return to Usual Health Among
Outpatients with COVID-19 in a Multistate Health Care Systems Network —
United States, March–June 2020. MMWR Morb Mortal Wkly Rep 2020;69:993-998.
· Tolba M, Abo Omirah M,
Hussein A, Saeed H. Assessment and Characterization of Post-COVID-19
manifestations. Int J Clin Pract. 2020 Sep 29:e13746
· https://evidence.nihr.ac.uk/themedreview/living-with-covid19/ (accessed Oct. 22, 2020)
· https://www.thephysician.uk/editorial-after-the-pandemic (accessed
Oct. 23, 2020)
· Long COVID: let patients
help define long-lasting COVID symptoms. Nature. 2020 Oct;586(7828):170
· Townsend L, Dyer AH et al. Persistent fatigue following
SARS-CoV2-infection is common and independent of severity of initial
infection. medRxiv https://www.medrxiv.org/content/10.1101/2020.07.29.20164293v1 (accessed
Oct. 23, 2020)
|
Dyspnea/ breathlessness
|
· Del Rio C, Collins LF,
Malani P. Long-term Health Consequences of COVID-19. JAMA. 2020 Oct 5. doi:
10.1001/jama.2020.19719
· Greenhalgh T, Knight M,
A'Court C, Buxton M, Husain L. Management of post-acute covid-19 in primary
care. BMJ. 2020 Aug 11;370:m3026.
· Carfì A, Bernabei R, Landi
F; Gemelli Against COVID-19 Post-Acute Care Study Group. Persistent Symptoms
in Patients After Acute COVID-19. JAMA. 2020 Aug 11;324(6):603-605.
· https://evidence.nihr.ac.uk/themedreview/living-with-covid19/ (accessed Oct. 22, 2020)
· Long COVID: let patients
help define long-lasting COVID symptoms. Nature. 2020 Oct;586(7828):170
|
Cough
|
· Greenhalgh T, Knight M,
A'Court C, Buxton M, Husain L. Management of post-acute covid-19 in primary
care. BMJ. 2020 Aug 11;370:m3026.
· Carfì A, Bernabei R, Landi
F; Gemelli Against COVID-19 Post-Acute Care Study Group. Persistent Symptoms
in Patients After Acute COVID-19. JAMA. 2020 Aug 11;324(6):603-605.
|
Chest pain/ heaviness
|
· Greenhalgh T, Knight M,
A'Court C, Buxton M, Husain L. Management of post-acute covid-19 in primary
care. BMJ. 2020 Aug 11;370:m3026
· Carfì A, Bernabei R, Landi
F; Gemelli Against COVID-19 Post-Acute Care Study Group. Persistent Symptoms
in Patients After Acute COVID-19. JAMA. 2020 Aug 11;324(6):603-605.
· https://evidence.nihr.ac.uk/themedreview/living-with-covid19/ (accessed Oct. 22, 2020)
· Long COVID: let patients
help define long-lasting COVID symptoms. Nature. 2020 Oct;586(7828):170
|
Joint pain/ muscle pain
|
· Carfì A, Bernabei R, Landi
F; Gemelli Against COVID-19 Post-Acute Care Study Group. Persistent Symptoms
in Patients After Acute COVID-19. JAMA. 2020 Aug 11;324(6):603-605.
· Long COVID: let patients
help define long-lasting COVID symptoms. Nature. 2020 Oct;586(7828):170
|
Chemosensory disturbances
(persistent loss of sense of smell
and taste)
|
· Del Rio C, Collins LF,
Malani P. Long-term Health Consequences of COVID-19. JAMA. 2020 Oct 5. doi:
10.1001/jama.2020.19719
· Greenhalgh T, Knight M,
A'Court C, Buxton M, Husain L. Management of post-acute covid-19 in primary
care. BMJ. 2020 Aug 11;370:m3026.
· Carfì A, Bernabei R, Landi
F; Gemelli Against COVID-19 Post-Acute Care Study Group. Persistent Symptoms
in Patients After Acute COVID-19. JAMA. 2020 Aug 11;324(6):603-605
|
Cognitive blunting (“brain
fog”)/ loss of concentration
|
· Del Rio C, Collins LF,
Malani P. Long-term Health Consequences of COVID-19. JAMA. 2020 Oct 5. doi:
10.1001/jama.2020.19719
· Greenhalgh T, Knight M,
A'Court C, Buxton M, Husain L. Management of post-acute covid-19 in primary
care. BMJ. 2020 Aug 11;370:m3026.
· Carfì A, Bernabei R, Landi
F; Gemelli Against COVID-19 Post-Acute Care Study Group. Persistent Symptoms
in Patients After Acute COVID-19. JAMA. 2020 Aug 11;324(6):603-605
|
Emotional health and
well-being:
·
|
· Del Rio C, Collins LF,
Malani P. Long-term Health Consequences of COVID-19. JAMA. 2020 Oct 5. doi:
10.1001/jama.2020.19719
· Greenhalgh T, Knight M,
A'Court C, Buxton M, Husain L. Management of post-acute covid-19 in primary
care. BMJ. 2020 Aug 11;370:m3026.
· https://evidence.nihr.ac.uk/themedreview/living-with-covid19/ (accessed Oct. 22, 2020)
· Vindegaard N, Benros ME.
COVID-19 pandemic and mental health consequences: Systematic review of the
current evidence. Brain Behav Immun. 2020 Oct;89:531-542.
· Vittori A, Lerman J,
Cascella M, Gomez-Morad AD, Marchetti G, Marinangeli F, Picardo SG. COVID-19
Pandemic Acute Respiratory Distress Syndrome Survivors: Pain After the Storm?
Anesth Analg. 2020 Jul;131(1):117-119
· Leung TYM, Chan AYL, Chan
EW, Chan VKY, Chui CSL, Cowling BJ, Gao L, Ge MQ, Hung IFN, Ip MSM, Ip P, Lau
KK, Lau CS, Lau LKW, Leung WK, Li X, Luo H, Man KKC, Ng VWS, Siu CW, Wan EYF,
Wing YK, Wong CSM, Wong KHT, Wong ICK. Short- and potential long-term adverse
health outcomes of COVID-19: a rapid review. Emerg Microbes Infect. 2020
Dec;9(1):2190-2199
|
Skin rashes:
|
· Greenhalgh T, Knight M,
A'Court C, Buxton M, Husain L. Management of post-acute covid-19 in primary
care. BMJ. 2020 Aug 11;370:m3026
· Skin rash should be
considered a 4th key sign of COVID-19 https://covid.joinzoe.com/us-post/skin-rash-covid (accessed Oct. 23, 2020)
|
Other:
|
· Greenhalgh T, Knight M,
A'Court C, Buxton M, Husain L. Management of post-acute covid-19 in primary
care. BMJ. 2020 Aug 11;370:m3026.
· Carfì A, Bernabei R, Landi
F; Gemelli Against COVID-19 Post-Acute Care Study Group. Persistent Symptoms
in Patients After Acute COVID-19. JAMA. 2020 Aug 11;324(6):603-605
|
Mitochrondia
Support
|
· Burtscher J, Cappellano G, Omori A, Koshiba T, Millet GP.
Mitochondria: In the Cross Fire of SARS-CoV-2 and Immunity. iScience. 2020
Oct 23;23(10):101631
· Saleh J, Peyssonnaux C, Singh KK, Edeas M. Mitochondria
and microbiota dysfunction in COVID-19 pathogenesis. Mitochondrion. 2020
Sep;54:1-7.
· Singh KK, Chaubey G, Chen JY, Suravajhala P. Decoding
SARS-CoV-2 hijacking of host mitochondria in COVID-19 pathogenesis. Am J
Physiol Cell Physiol. 2020 Aug 1;319(2):C258-C267.
· Kloc M, Ghobrial RM, Kubiak JZ. The Role of Genetic Sex
and Mitochondria in Response to COVID-19 Infection. Int Arch Allergy Immunol.
2020;181(8):629-634
· Halpin SJ, McIvor C, Whyatt G, Adams A, Harvey O, McLean
L, Walshaw C, Kemp S, Corrado J, Singh R, Collins T, O'Connor RJ, Sivan M.
Postdischarge symptoms and rehabilitation needs in survivors of COVID-19
infection: A cross-sectional evaluation. J Med Virol. 2020 Jul 30. doi:
10.1002/jmv.26368.
· European Respiratory Journal 2020; 56: Suppl. 64, 4143.
https://erj.ersjournals.com/content/56/suppl_64/4143.abstract (accessed Niv
6, 2020)
· Ojo AS, Balogun SA, Williams OT, Ojo OS. Pulmonary
Fibrosis in COVID-19 Survivors: Predictive Factors and Risk Reduction
Strategies. Pulm Med. 2020 Aug 10;2020:6175964
· Li G, Hu R, Gu X. A close-up on COVID-19 and
cardiovascular diseases. Nutr Metab Cardiovasc Dis. 2020 Jun 25;30(7):1057-1060
· Boukhris M, Hillani A, Moroni F, Annabi MS,
Addad F, Ribeiro MH, Mansour S, Zhao X, Ybarra LF, Abbate A, Vilca LM,
Azzalini L. Cardiovascular Implications of the COVID-19 Pandemic: A Global
Perspective. Can J Cardiol. 2020 Jul;36(7):1068-1080
|
Specific organ
dysfunction (heart):
·
|
· Del Rio C, Collins LF,
Malani P. Long-term Health Consequences of COVID-19. JAMA. 2020 Oct 5. doi:
10.1001/jama.2020.19719
· Greenhalgh T, Knight M,
A'Court C, Buxton M, Husain L. Management of post-acute covid-19 in primary
care. BMJ. 2020 Aug 11;370:m3026
· Tolba M, Abo Omirah M,
Hussein A, Saeed H. Assessment and Characterization of Post-COVID-19
manifestations. Int J Clin Pract. 2020 Sep 29:e13746
· Leung TYM, Chan AYL, Chan
EW, Chan VKY, Chui CSL, Cowling BJ, Gao L, Ge MQ, Hung IFN, Ip MSM, Ip P, Lau
KK, Lau CS, Lau LKW, Leung WK, Li X, Luo H, Man KKC, Ng VWS, Siu CW, Wan EYF,
Wing YK, Wong CSM, Wong KHT, Wong ICK. Short- and potential long-term adverse
health outcomes of COVID-19: a rapid review. Emerg Microbes Infect. 2020
Dec;9(1):2190-2199
· https://evidence.nihr.ac.uk/themedreview/living-with-covid19/ (accessed Oct. 22, 2020)
· https://www.thephysician.uk/editorial-after-the-pandemic (accessed
Oct. 23, 2020)
· Long COVID and inflammation: a cardiologists point of
view https://www.medscape.com/viewarticle/935488#vp_2 (accessed
Oct 23, 2020)
· Note: the reduction in heart pumping after recovering from
COVID-19 may be more common in men according to preliminary results from the
COVERSCAN study https://www.itv.com/news/2020-08-12/long-covid-what-is-it-what-are-the-symptoms-and-what-help-is-there-for-sufferers (accessed
OCT 23, 2020)
|
Specific organ
dysfunction (lung):
·
|
· Del Rio C, Collins LF,
Malani P. Long-term Health Consequences of COVID-19. JAMA. 2020 Oct 5. doi:
10.1001/jama.2020.19719
· Greenhalgh T, Knight M,
A'Court C, Buxton M, Husain L. Management of post-acute covid-19 in primary
care. BMJ. 2020 Aug 11;370:m3026
· Tolba M, Abo Omirah M,
Hussein A, Saeed H. Assessment and Characterization of Post-COVID-19
manifestations. Int J Clin Pract. 2020 Sep 29:e13746
· Leung TYM, Chan AYL, Chan
EW, Chan VKY, Chui CSL, Cowling BJ, Gao L, Ge MQ, Hung IFN, Ip MSM, Ip P, Lau
KK, Lau CS, Lau LKW, Leung WK, Li X, Luo H, Man KKC, Ng VWS, Siu CW, Wan EYF,
Wing YK, Wong CSM, Wong KHT, Wong ICK. Short- and potential long-term adverse
health outcomes of COVID-19: a rapid review. Emerg Microbes Infect. 2020
Dec;9(1):2190-2199
· https://evidence.nihr.ac.uk/themedreview/living-with-covid19/ (accessed Oct. 22, 2020)
· https://www.thephysician.uk/editorial-after-the-pandemic (accessed
Oct. 23, 2020)
|
Specific organ
dysfunction (brain):
·
|
· Del Rio C, Collins LF,
Malani P. Long-term Health Consequences of COVID-19. JAMA. 2020 Oct 5. doi:
10.1001/jama.2020.19719
· Greenhalgh T, Knight M,
A'Court C, Buxton M, Husain L. Management of post-acute covid-19 in primary
care. BMJ. 2020 Aug 11;370:m3026.
· Carfì A, Bernabei R, Landi
F; Gemelli Against COVID-19 Post-Acute Care Study Group. Persistent Symptoms
in Patients After Acute COVID-19. JAMA. 2020 Aug 11;324(6):603-605
· Greenhalgh T, Knight M,
A'Court C, Buxton M, Husain L. Management of post-acute covid-19 in primary
care. BMJ. 2020 Aug 11;370:m3026.
|
Specific organ
dysfunction (kidney):
|
· https://www.thephysician.uk/editorial-after-the-pandemic (accessed
Oct. 23, 2020)
· Tolba M, Abo Omirah M,
Hussein A, Saeed H. Assessment and Characterization of Post-COVID-19
manifestations. Int J Clin Pract. 2020 Sep 29:e13746
· Prelimary results from the
COVERSCAN study in Oxford https://www.itv.com/news/2020-09-29/long-covid-long-term-effects-of-coronavirus-include-damage-to-heart-liver-kidneys-oxford-study-reveals (accessed Oct. 23, 2020)
|
Other
Research
|
· Carfì A, Bernabei R, Landi F; Gemelli Against COVID-19 P ost-Acute
Care Study Group. Persistent Symptoms in Patients After Acute COVID-19. JAMA.
2020 Aug 11;324(6):603-605.
·
Tenforde
MW, Kim SS, Lindsell CJ, et al. Symptom Duration and Risk Factors for Delayed
Return to Usual Health Among Outpatients with COVID-19 in a Multistate Health
Care Systems Network — United States, March–June 2020. MMWR Morb Mortal Wkly
Rep 2020;69:993-998.
·
Zhou H, Lu
S, Chen J, Wei N, Wang D, Lyu H, Shi C, Hu S. The landscape of cognitive
function in recovered COVID-19 patients. J Psychiatr Res. 2020 Oct;129:98-102
·
Hascup ER,
Hascup KN. Does SARS-CoV-2 infection cause chronic neurological
complications? Geroscience. 2020 Aug;42(4):1083-1087.
·
Troyer EA,
Kohn JN, Hong S. Are we facing a crashing wave of neuropsychiatric sequelae
of COVID-19? Neuropsychiatric symptoms and potential immunologic mechanisms.
Brain Behav Immun. 2020 Jul;87:34-39.
·
Steardo L
Jr, Steardo L, Verkhratsky A. Psychiatric face of COVID-19. Transl
Psychiatry. 2020 Jul 30;10(1):261.
·
Alam SB,
Willows S, Kulka M, Sandhu JK. Severe acute respiratory syndrome coronavirus
2 may be an underappreciated pathogen of the central nervous system. Eur J
Neurol. 2020 Jul 15:10.1111/ene.14442.
·
Heneka MT,
Golenbock D, Latz E, Morgan D, Brown R. Immediate and long-term consequences
of COVID-19 infections for the development of neurological disease.
Alzheimers Res Ther. 2020 Jun 4;12(1):69.
·
Salimi S,
Hamlyn JM. COVID-19 and Crosstalk With the Hallmarks of Aging. J Gerontol A
Biol Sci Med Sci. 2020 Sep 16;75(9):e34-.
·
Disser NP,
De Micheli AJ, Schonk MM, Konnaris MA, Piacentini AN, Edon DL, Toresdahl BG,
Rodeo SA, Casey EK, Mendias CL. Musculoskeletal Consequences of COVID-19. J
Bone Joint Surg Am. 2020 Jul 15;102(14):1197-1204.
·
Azim D,
Nasim S, Kumar S, Hussain A, Patel S. Neurological Consequences of 2019-nCoV
Infection: A Comprehensive Literature Review. Cureus. 2020 Jun
24;12(6):e8790.
·
Kaniusas
E, Szeles JC, Kampusch S, Alfageme-Lopez N, Yucuma-Conde D, Li X, Mayol J,
Neumayer C, Papa M, Panetsos F. Non-invasive Auricular Vagus Nerve
Stimulation as a Potential Treatment for Covid19-Originated Acute Respiratory
Distress Syndrome. Front Physiol. 2020 Jul 28;11:890.
·
Kempuraj
D, Selvakumar GP, Ahmed ME, Raikwar SP, Thangavel R, Khan A, Zaheer SA, Iyer
SS, Burton C, James D, Zaheer A. COVID-19, Mast Cells, Cytokine Storm,
Psychological Stress, and Neuroinflammation. Neuroscientist. 2020
Oct-Dec;26(5-6):402-414.
·
Conti P, Caraffa A, Tetè G, Gallenga CE, Ross R, Kritas SK,
Frydas I, Younes A, Di Emidio P, Ronconi G. Mast cells activated by
SARS-CoV-2 release histamine which increases IL-1 levels causing cytokine
storm and inflammatory reaction in COVID-19. J Biol Regul Homeost Agents.
2020 Sep-Oct,;34(5):1629-1632.
·
Shaik Y, caraffa A, Ronconi G, Lessiani G, Conti P. Impact
of polyphenols on mast cells with special emphasis on the effect of quercetin
and luteolin. Cent Eur J. Immunol. 2018;43(4):476-481)
·
Akour A.
Probiotics and COVID-19: is there any link? Lett Appl Microbiol. 2020
Sep;71(3):229-234.
·
Saleh J,
Peyssonnaux C, Singh KK, Edeas M. Mitochondria and microbiota dysfunction in
COVID-19 pathogenesis. Mitochondrion. 2020 Sep;54:1-7.
·
Dhar D, Mohanty A. Gut microbiota and Covid-19- possible
link and implications. Virus Res. 2020 Aug;285:198018.
·
Baghbani T, Nikzad H, Azadbakht J, Izadpanah F, Haddad
Kashani H. Dual and mutual interaction between microbiota and viral
infections: a possible treat for COVID-19. Microb Cell Fact. 2020 Nov
26;19(1):217.
·
Baumann
A, Gönnenwein S, Bischoff SC, Sherman H, Chapnik N, Froy O, Lorentz A. The
circadian clock is functional in eosinophils and mast cells. Immunology. 2013
Dec;140(4):465-74
|